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Sample Analysis and Processing

Gene Expression Profiling and Copy Number Variation

Gene Expression Profiling

We offer low-, medium- and high-throughput options for gene expression and gene copy number analysis of human and mouse samples. Array-comparative genomic hybridization (Array CGH) enables high-resolution detection of genomic copy number variants. Differentially labeled reference and experimental samples are hybridized to microarrays, allowing detection of structural variants as small as 200bp. We offer pre-validated assay panels as well as the capacity to design and validate custom panels. Our platforms include both traditional qPCR-based detection and high-throughput microfluidic chips and microarrays, all with fully automated processing.

Low to Medium Throughput Gene Expression Services

Solutions for tens to hundreds of samples and tens to hundreds of target genes.


  • Capabilities
    • Automated DNA and RNA extraction for a variety of primary sample types (tissue, whole blood, FFPE, cells)
    • Integrated sample and data QC
    • Automated liquid-handling for PCR reaction setup
    • Variety of chemistries available: Taqman®, SYBR Green, Universal ProbeLibrary
    • Assay design and wet bench validation at no additional cost
    • Differential expression analysis and reports provided
  • Technologies
    • Applied Biosystems ViiA™ 7 Real-Time PCR System- This high performance instrument delivers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation. This system combines 96- and 384-well formats with fully automated robotic plate loading for high-productivity real-time PCR processing.
    • Fluidigm BioMarkTM System using 96.96 and 48.48 Dynamic Arrays – capable of 9,200 real-time qPCR reactions in picoliter volumes in a single run. Digital PCR arrays enable ultrahigh-resolution and absolute molecule quantification for gene copy number experiments.
    • WafergenTM SmartChip catalog and MyDesignTM Arrays – capable of 5000+ real-time qPCR reactions with flexible sample and assay formats

High Throughput Gene Expression Services

Medium Throughput Genotyping

Microarray solutions for transcriptomics and genome-wide expression analysis.


  • Capabilities
    • Automated DNA and RNA extraction for a variety of primary sample types (tissue, whole blood, FFPE, cells)
    • Integrated sample and data QC
    • Whole-transcriptome amplification (WTA) services for limited amounts of precious RNA samples
    • Automated microarray sample processing and array development
    • Bioinformatics services for in depth microarray analysis, visualization and interpretation of results
  • Technologies
  • RUCDR Infinite Biologics offers high throughput microarray-based solutions for gene profiling studies. All sample preparation protocols are fully automated to ensure contaminant-free, robust gene expression analysis across platforms. Integrated sample management, nucleic acid extraction, microarray and analysis service bundles are available.
    • Affymetrix GeneChip and GeneTitan Systems for all Affymetrix gene profiling products
    • Illumina iScan System for all Illumina microarray products
    • Agilent CGH arrays, Invitrogen NCode arrays
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145 Bevier Road Piscataway NJ 08854-8009
p 732 445 1498 f 732 445 1149 www.rucdr.org