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Sample Analysis and Processing

Genotyping Services

Genotyping Services

We offer pre-validated genotyping panels for human and mouse samples as well as the capacity to design and validate custom panels. Our platforms include both traditional qPCR-based detection and high-throughput microfluidic chips and arrays, all with fully-automated processing.

Low Throughput Genotyping

Genotyping solutions for tens of samples for tens of targets


  • Capabilities
    • Automated DNA extraction (small, medium, large scale)
    • Integrated sample and data QC
    • Automated liquid-handling for PCR reaction setup
    • Variety of chemistries available: Taqman®, SNPtype, Somatic Mutation
    • Assay design and wet bench validation at no additional cost
    • Genotyping reports included
  • Technologies
    • Allelic Discrimination, SNPtypeTM and Amplification Refractory Mutation chemistries utilized for genotype and somatic mutation analysis. All reactions are setup using sophisticated liquid handling instruments to minimize variation and ensure high quality data.
    • ABI 7900HT  - This Fast Real-Time PCR System combines 96- and 384-well formats with fully automated robotic loading and fast real-time PCR capability.
    • ViiATM 7 Instruments - This high performance instrument delivers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation for high-productivity real-time PCR processing.

Medium Throughput Genotyping

Medium Throughput Genotyping

Genotyping solutions for hundreds of samples for hundreds to thousands of targets


  • Capabilities
    • Automated DNA extraction (small, medium, large scale)
    • Integrated sample and data QC
    • Automated liquid-handling for PCR reaction setup
    • Variety of chemistries available: Taqman®, SNPtypeTM, Somatic Mutation
    • Assay design and wet bench validation at no additional cost
    • Custom assay designs and catalog array formats for BioMarkTM and WaferGenTM systems
    • Automated genotype calling and performance metrics for all platforms
    • Genotyping reports included
  • Technologies: Automated Allelic Discrimination
  • Automated high-throughput, small-volume PCR technologies are provided to support medium throughput SNP genotyping and copy number variation analyses. Automated reaction preparation protects against sample contamination and ensures robust and reproducible data generation.
    • ABI 7900HT or ViiATM 7 Instruments
      Fluidigm BioMarkTM System using 96.96 and 48.48 Dynamic Arrays – capable of 9,200 genotypes in picoliter volumes in 90 min.
    • WafergenTM SmartChip Catalogue and MyDesignTM Arrays – capable of 5000+ genotypes in any sample or assay format desired.
    • Beckman Coulter GenomeLabTM SNPstream® Genotyping System - capable of performing from 4,600 to over 3,000,000 SNP genotypes per day.

High Throughput Genotyping

High Throughput Genotyping

Genotyping for thousands of samples for hundreds/thousands of targets and/or whole genome analyses.


  • Capabilities
    • Automated DNA extraction (small, medium, large scale)
    • Integrated sample and data QC
    • Automated liquid handling for PCR reaction set up
    • Taqman® Array, SmartChip and BioMarkTM array design and validation
    • Assay design and wet bench validation included at no additional cost
    • Custom designed assay panels for Ion Personal Genome Machine® and Illumina MiSeq NextGen sequencing (including variant calls)
    • Automated genotype calling and performance metrics for all platforms
    • Automated microarray sample processing and array development
    • Automated library prep for NextGen sequencing based genotyping
    • Genotyping reports included
  • Technologies
  • RUCDR Infinite Biologics offers high throughput genotyping technologies for PCR, microarray and NextGen sequencing. All sample preparation protocols are fully automated to ensure contaminant-free, robust genotyping analysis across platforms. Integrated sample management, nucleic acid extraction and genotyping service bundles are available.
    • Taqman Arrays using ViiATM 7 Instruments
    • Affymetrix GeneChip and GeneTitan Systems for all Affymetrix genotyping products
    • Illumina iScan Systems for all Illumina genotyping products
    • Ion Torrent PGMTM targeted sequencing panels
    • Illumina MiSeq targeted sequencing panels
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145 Bevier Road Piscataway NJ 08854-8009
p 732 445 1498 f 732 445 1149 www.rucdr.org